SLC16A3 antibody (AA 40-89)

Catalog No. ABIN6746227

Product Details anti-SLC16A3 Antibody

Target: SLC16A3 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3))

Binding Specificity: AA 40-89

Reactivity: Human, Mouse, Rat, Cow, Dog, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC16A3 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Mouse SLC16A3

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Xenopus (92%) Mouse, Rat, Dog, Bovine, Rabbit, Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa40-89 of mouse Slc16a3 (P57787, NP_109621). Percent identity by BLAST analysis: Human, Gorilla, Mouse (100%), Orangutan, Gibbon, Elephant, Horse, Opossum, Zebra finch, Platypus, Xenopus (92%), Monkey, Marmoset, Rat, Hamster, Dog, Bovine, Rabbit, Guinea pig, Turkey, Chicken, Zebrafish (85%), Panda (84%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: WB (1 μg/mL)

Usage: Western Blot: Suggested dilution at 1 μg/mL in 5 % skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

References for anti-SLC16A3 antibody (ABIN6746227)

Vargas, Nore, Berglof, Heinonen, Mattsson, Smith, Mohamed: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." in: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).

Rajantie, Ekman, Iljin, Arighi, Gunji, Kaukonen, Palotie, Dewerchin, Carmeliet, Alitalo: "Bmx tyrosine kinase has a redundant function downstream of angiopoietin and vascular endothelial growth factor receptors in arterial endothelium." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4647-55, (2001) (PubMed).

Kaukonen, Lahtinen, Laine, Alitalo, Palotie: "BMX tyrosine kinase gene is expressed in granulocytes and myeloid leukaemias." in: British journal of haematology, Vol. 94, Issue 3, pp. 455-60, (1996) (PubMed).

Target Details for SLC16A3

Target: SLC16A3 (Solute Carrier Family 16 (Monocarboxylic Acid Transporters), Member 3 (SLC16A3))

Alternative Name: SLC16A3 / MCT4 (SLC16A3 Products)

Background: Name/Gene ID: SLC16A3
Subfamily: Monocarboxylic acid transporter
Family: Transporter

Synonyms: SLC16A3, MCT 3, MCT-4, MCT3, MCT4, Monocarboxylate transporter 4, MCT-3, Monocarboxylate transporter 3, MCT 4

Gene ID: 9123

NCBI Accession: NP_109621

UniProt: O15427

Pathways: Warburg Effect