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CD70 antibody

CD70 Reactivity: Human ELISA, FACS, IHC, IHC (fro), ICC, Func Host: Mouse Monoclonal BU69 unconjugated
Catalog No. ABIN610194
  • Target See all CD70 Antibodies
    CD70 (CD70 Molecule (CD70))
    Reactivity
    • 93
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 61
    • 32
    • 5
    • 2
    • 1
    Mouse
    Clonality
    • 61
    • 39
    • 1
    Monoclonal
    Conjugate
    • 52
    • 11
    • 9
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD70 antibody is un-conjugated
    Application
    • 48
    • 45
    • 43
    • 36
    • 22
    • 19
    • 17
    • 12
    • 11
    • 9
    • 8
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC), Functional Studies (Func)
    Specificity
    CD70 Molecule of approximately 30 kd.
    Purification
    Protein A purified
    Immunogen
    Human WM-1 (Waldenstrpm's macroglobulinemia) cell line.
    Clone
    BU69
    Isotype
    IgG1
    Top Product
    Discover our top product CD70 Primary Antibody
  • Application Notes
    Approved: ELISA, Flo, Func, ICC, IHC, IHC-Fr

    Usage: Function: Blocks the interaction between CD27 and CD70, and has been shown to inhibit T cell proliferation induced by dendritic cells.
    Comment

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride, 0.5 mg/mL Gentamicin sulfate
    Preservative
    Gentamicin sulfate
    Precaution of Use
    This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Do not freeze.
    Storage
    4 °C
    Storage Comment
    Store at 4°C. Do not freeze.
  • Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

    Huan, van Adelsberg: "Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins." in: The Journal of clinical investigation, Vol. 104, Issue 10, pp. 1459-68, (1999) (PubMed).

  • Target
    CD70 (CD70 Molecule (CD70))
    Alternative Name
    CD70 (CD70 Products)
    Background
    Name/Gene ID: CD70
    Family: TNF

    Synonyms: CD70, CD27LG, Ki-24 antigen, Surface antigen CD70, CD27 ligand, CD27-L, CD70 antigen, CD70 Molecule, TNFSF7
    Gene ID
    970
    UniProt
    P32970
    Pathways
    Cancer Immune Checkpoints
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