FCGR1A antibody

Catalog No. ABIN610183

Product Details anti-FCGR1A Antibody

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Fragment: F(ab')2 fragment

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Functional Studies (Func)

Specificity: CD64 Molecule of 72 kd from gene Fc gamma RIA.

Purification: Protein A purified

Immunogen: Human rheumatoid synovial fluid cells/monocytes.

Type of Immunogen: Cells

Clone: 10-1

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, Func, WB

Usage: Function: Blocks binding of Fc gamma RI to immunoglobulin opsonized cells. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 100 mM potassium chloride, 150 mM sodium chloride

Handling Advice: Do not freeze. Open under aseptic conditions.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Open under aseptic conditions.

References for anti-FCGR1A antibody (ABIN610183)

Natsugoe, Nakashima, Matsumoto, Xiangming, Okumura, Kijima, Ishigami, Takebayashi, Baba, Takao, Aikou: "Expression of p21WAF1/Cip1 in the p53-dependent pathway is related to prognosis in patients with advanced esophageal carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 5, Issue 9, pp. 2445-9, (1999) (PubMed).

Hurd, Khattree, Alban, Nag, Jhanwar, Dinda, Moudgil: "Hormonal regulation of the p53 tumor suppressor protein in T47D human breast carcinoma cell line." in: The Journal of biological chemistry, Vol. 270, Issue 48, pp. 28507-10, (1996) (PubMed).

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: FCGR1A / CD64 (FCGR1A Products)

Background: Name/Gene ID: FCGR1A

Synonyms: FCGR1A, CD64A, CD64, CD64 antigen, FCG1, FcgammaRIa, IGFR1, IgG Fc receptor I, Fc-gamma receptor I A1, Fc-gamma RIA, FCGR1, Fc gamma receptor, Fc-gamma RI, FCRI

Gene ID: 2209

UniProt: P12314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process