CXCR4 antibody (AA 18-33)

Catalog No. ABIN609469

Product Details anti-CXCR4 Antibody

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Binding Specificity: AA 18-33

Reactivity: Human, Cow, Dog, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes human C-X-C Chemokine receptor 4 at 40kD. Species cross-reactivity: rat. Sequence Homology: mouse.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Chimpanzee, Tamarin, Sheep, Panda, Bovine, Dog, Cat (100%) Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse, Pig (94%) Mouse, Rat (88%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide corresponding to aa18-33, SGDYDSMKEPCFREEN to human C-X-C Chemokine receptor 4. Percent identity by BLAST analysis: Human, Chimpanzee, Tamarin, Sheep, Panda, Bovine, Dog, Cat (100%), Gorilla, Orangutan, Gibbon, Baboon, Monkey, Marmoset, Elephant, Bat, Rabbit, Horse, Pig (94%), Mouse, Rat (88%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (2 μg/mL), WB (1 μg/mL)

Usage: Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1 μg/mL. Immunohistochemistry (paraffin and formalin): 2.0 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: 10 μL sterile ddH2O

Concentration: Lot specific

Buffer: Lyophilized from PBS, 5 % BSA, 0.05 % Thimeorsal, 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Aliquot to Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Lyophilized powder may be stored at -20°C. Stable for 1 year at -20°C. Aliquot to avoid freeze-thaw cycles. Store at -20°C. Reconstituted product is stable for 1 year at -20°C.

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4 (CXCR4 Products)

Background: Name/Gene ID: CXCR4
Subfamily: Chemokine
Family: GPCR

Synonyms: CXCR4, CD184, CD184 antigen, Cmkar4, Cxc chemokine receptor 4, CXCR-4, CXC-R4, D2S201E, FB22, Fusin, HM89, LCR1, NPY3R, NPYRL, NPYY3R, Npyy3, HSY3RR, SDF-1 receptor, WHIM, C-x-c chemokine receptor 4, LESTR, Neuropeptide Y receptor Y3, NPYR

Gene ID: 7852

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events