Integrin Alpha2b antibody (PE)
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- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Reactivity
- Human, Baboon, Mink
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Specificity
- Recognizes the human CD41 cell surface antigen, a 140kD glycoprotein expressed by platelets and megakaryocytes. CD41 is also known as platelet glycoprotein IIb, and functions as a receptor for fibrinogen, fibronectin and vWF. It has not been established if clone Recognizes free CD41 or CD41 only when complexed with CD61. However, antibody binding is reduced in the presence of EDTA suggesting that the epitope recognized is dependent upon an intact CD41/61 complex.
- Purification
- Ion exchange chromatography
- Immunogen
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Human platelet plasma membrane.
Type of Immunogen: Membrane preparation - Isotype
- IgG1
- Top Product
- Discover our top product CD41 Primary Antibody
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- Application Notes
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Approved: Flo (1:1)
Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 100 μL whole blood. Method sheets are available on request. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute with 1 mL distilled water.
- Concentration
- Lot specific
- Buffer
- Lyophilized PBS, 0.09 % sodium azide, 1 % BSA, 5 % sucrose
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze. Product is photosensitive and should be protected from light. Store undiluted.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C. Do not freeze. Protect from light. Store undiluted.
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- ITGA2B / CD41 (CD41 Products)
- Background
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Name/Gene ID: ITGA2B
Family: Integrin
Synonyms: ITGA2B, BDPLT2, CD41B, GT, gp2B, Integrin alpha-IIb, ITGAB, GPIIb, HPA3, Platelet-specific antigen BAK, CD41, CD41 antigen, GPalpha IIb, GTA - Gene ID
- 3674
- UniProt
- P08514
- Pathways
- Integrin Complex
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