Cyclin A antibody (Biotin)
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- Target See all Cyclin A (CCNA2) Antibodies
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Cyclin A antibody is conjugated to Biotin
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Application
- Western Blotting (WB), Immunoprecipitation (IP)
- Specificity
- This antibody reacts with Cyclin A (55 kDa).
- Purification
- Protein-A Agarose Chromatography of hybridoma supernatant.
- Immunogen
- Bovine recombinant Cyclin A.
- Clone
- E67-1
- Isotype
- IgG2a
- Top Product
- Discover our top product CCNA2 Primary Antibody
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anti-Cyclin A2 (CCNA2) antibody
KO Validated CCNA2 Reactivity: Human WB, IF, IHC (p), IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 105-233) antibodyCCNA2 Reactivity: Human WB, IHC, ELISA, FACS Host: Mouse Monoclonal 6B4D11 unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84), (N-Term) antibodyCCNA2 Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB14617 unconjugated
anti-Cyclin A2 (CCNA2) (AA 1-200) antibodyCCNA2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 51-84) antibodyCCNA2 Reactivity: Human WB, IHC, ELISA, FACS Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (AA 375-431) antibodyCCNA2 Reactivity: Human, Mouse WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 Reactivity: Human, Mouse, Rat WB, IHC, IF, ELISA, ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 Reactivity: Human ELISA, IP Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) (C-Term) antibodyCCNA2 Reactivity: Human, Mouse WB, IF, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
anti-Cyclin A2 (CCNA2) antibodyCCNA2 Reactivity: Human, Mouse, Cow, Green Monkey, Mink IHC, IF, FACS, StM Host: Mouse Monoclonal E67 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 20 µg/mL
- Buffer
- PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store the antibody (in aliquots) at -20 °C.
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- Target
- Cyclin A (CCNA2) (Cyclin A2 (CCNA2))
- Alternative Name
- Cyclin A2 (CCNA2 Products)
- Background
- Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2
- Gene ID
- 890
- NCBI Accession
- NP_001228
- UniProt
- P20248
- Pathways
- PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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