CXCR4 antibody (AA 1-46)

Catalog No. ABIN521674

Product Details anti-CXCR4 Antibody

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Binding Specificity: AA 1-46

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CXCR4 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Mouse monoclonal antibody raised against a partial recombinant CXCR4.

Sequence: MEGISIYTSD NYTEEMGSGD YDSMKEPCFR EENANFNKIF LPTIYS

Cross-Reactivity: Human, Rat

Characteristics: Antibody Reactive Against Recombinant Protein.

Immunogen: CXCR4 (AAH20968, 1 a.a. ~ 46 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Clone: 2G9

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: In 1x PBS, pH 7.4

Handling Advice: Aliquot to avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

References for anti-CXCR4 antibody (ABIN521674)

Tripathi, Vana, Chavan, Brueggemann, Byron, Tarasova, Volkman, Gaponenko, Majetschak: "Heteromerization of chemokine (C-X-C motif) receptor 4 with ?1A/B-adrenergic receptors controls ?1-adrenergic receptor function." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 13, pp. E1659-68, (2015) (PubMed).

Target Details for CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Alternative Name: CXCR4 (CXCR4 Products)

Background: Full Gene Name: chemokine (C-X-C motif) receptor 4
Synonyms: CD184,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM

Gene ID: 7852

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events