LATS1 antibody (Middle Region)

Catalog No. ABIN504448

Product Details anti-LATS1 Antibody

Target: LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Zebrafish (Danio rerio), Cow, Saccharomyces cerevisiae, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LATS1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: IPPQAKLSPE ASDLIIKLCR GPEDRLGKNG ADEIKAHPFF KTIDFSSDLR

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 83%, Zebrafish: 86%

Characteristics: This is a rabbit polyclonal antibody against LATS1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LATS1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1130 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LATS1

Target: LATS1 (LATS, Large Tumor Suppressor, Homolog 1 (Drosophila) (LATS1))

Alternative Name: LATS1 (LATS1 Products)

Synonyms: WARTS antibody, wts antibody, AW208599 antibody, Lats antibody, si:dkey-181i3.5 antibody, wu:fc19a11 antibody, zgc:123219 antibody, lats1 antibody, RGD1564085 antibody, warts antibody, large tumor suppressor kinase 1 antibody, large tumor suppressor antibody, large tumor suppressor kinase 1 S homeolog antibody, LATS1 antibody, Lats1 antibody, lats1 antibody, lats1.S antibody

Background: The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late
Alias Symbols: WARTS, wts
Protein Interaction Partner: SPERT, KRT31, GOLGA2, FSD2, SSX2IP, CEP76, MOAP1, TFIP11, LDOC1, TRAF1, ITCH, HSP90AB1, AMOT, KIRREL, MOB1A, CEP192, LATS2, CEP152, CEP131, RAB35, SDCCAG3, YAP1, INADL, SEC16A, CCP110, TJP2, MAGI1, LIMD1, PKP4, OFD1, AMOTL1, CNTROB, MOB1B, LZTS2, MPP5, KI
Protein Size: 1130

Molecular Weight: 124 kDa

Gene ID: 9113

NCBI Accession: NM_004690, NP_004681

UniProt: O95835

Pathways: Regulation of Actin Filament Polymerization, Maintenance of Protein Location