PPM1B antibody (N-Term)

Catalog No. ABIN504355

Product Details anti-PPM1B Antibody

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Binding Specificity: N-Term

Reactivity: Human, Rat, Mouse, Dog, Horse, Cow, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EIMEKSGEEG MPDLAHVMRI LSAENIPNLP PGGGLAGKRN VIEAVYSRLN

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against PPM1B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PPM1B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 192 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPM1B

Target: PPM1B (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1B (PPM1B))

Alternative Name: PPM1B (PPM1B Products)

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent
Alias Symbols: MGC21657, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
Protein Interaction Partner: AURKB, VCP, SUMO2, SUMO3, UBC, SUMO1, GCH1, PAN2, Smurf2, NOS2, ECHS1, MAGOH, YWHAE, EIF4A3, UBL7, FBXO6, ARRB2, ARRB1, VAV2, TLE4, VHL, ISG15, CDK6, IKBKB, MAP3K7, MSN, IKBKG, CDK2, PPP2CA, CHUK, RASGRP1, PABPC4, VIL1, S100A8, KRT18, GSN, ANXA2, ANXA1,
Protein Size: 192

Molecular Weight: 21 kDa

Gene ID: 5495

NCBI Accession: NM_177969, NP_808908

UniProt: Q96ER6