PPM1A antibody (Middle Region)

Catalog No. ABIN504354

Product Details anti-PPM1A Antibody

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Zebrafish (Danio rerio), Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPM1A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EIDEHMRVMS EKKHGADRSG STAVGVLISP QHTYFINCGD SRGLLCRNRK

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against PPM1A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPM1A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 324 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PPM1A

Target: PPM1A (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1A (PPM1A))

Alternative Name: PPM1A (PPM1A Products)

Background: The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the acti
Alias Symbols: MGC9201, PP2C-ALPHA, PP2CA, PP2Calpha
Protein Interaction Partner: DCP1B, HSFY1, UBC, ASB2, RPLP0, HSPB1, NR4A1, FGFR2, SMURF1, SMAD1, ARRB2, ARRB1, SMAD3, DVL2, DVL3, SMAD2, DVL1, GRM3, CACNA1B, CACNA1A, MSN, PRKCD, PIK3R1, AKT1, EEF2, CTNNB1, CACNA1C, LXN,
Protein Size: 324

Molecular Weight: 36 kDa

Gene ID: 5494

NCBI Accession: NM_177951, NP_808820