RAN antibody (Middle Region)

Catalog No. ABIN504056

Product Details anti-RAN Antibody

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Zebrafish (Danio rerio), Pig, Sheep, Horse, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAN antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: NLQYYDISAK SNYNFEKPFL WLARKLIGDP NLEFVAMPAL APPEVVMDPA

Predicted Reactivity: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against RAN. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RAN

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 216 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RAN

Target: RAN (RAN, Member RAS Oncogene Family (RAN))

Alternative Name: RAN (RAN Products)

Background: RAN (ras-related nuclear protein) is a small GTP binding protein belonging to the RAS superfamily that is essential for the translocation of RNA and proteins through the nuclear pore complex. The RAN protein is also involved in control of DNA synthesis an
Alias Symbols: ARA24, Gsp1, TC4
Protein Interaction Partner: NUTF2, FUS, UBC, SUMO2, RANBP2, RANBP9, STAU1, ADRB2, SUMO1, NEDD8, MDM2, ASB16, ASB2, SUZ12, EED, RNF2, rev, PFDN4, PTMA, RANBP1, CDK2, rna1, PAN2, XPO5, VCAM1, RPL7, ITGA4, FN1, ESR1, CFTR, RGPD5, MAGOH, EIF4A3, KPNA2, CSE1L, TRA2B, TNPO1, KPNB1, RCC1,
Protein Size: 216

Molecular Weight: 24 kDa

Gene ID: 5901

NCBI Accession: NM_006325, NP_006316

UniProt: P62826

Pathways: Regulatory RNA Pathways, Intracellular Steroid Hormone Receptor Signaling Pathway, Protein targeting to Nucleus