Epsin 2 antibody (Middle Region)

Catalog No. ABIN503706

Product Details anti-Epsin 2 Antibody

Target: Epsin 2 (EPN2)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Epsin 2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: DPFESQPLTV ASSKPSSARK TPESFLGPNA ALVNLDSLVT RPAPPAQSLN

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against EPN2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPN2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 584 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Epsin 2

Target: Epsin 2 (EPN2)

Alternative Name: EPN2 (EPN2 Products)

Background: EPN2 is a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis.This gene encodes a protein which interacts with clathrin and adaptor-related protein complex 2, alpha 1 subunit. The protein is found in a brain-derived clathrin-coated vesicle fraction and localizes to the peri-Golgi region and the cell periphery. The protein is thought to be involved in clathrin-mediated endocytosis. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: EHB21, KIAA1065
Protein Interaction Partner: rev, UBC, APOE, UBQLN2, ITSN1, RNF11, EPS15, YWHAG, TUBA1B, LAPTM5, CLTC, TFAP2A, Eps15l1,
Protein Size: 584

Molecular Weight: 62 kDa

Gene ID: 22905

NCBI Accession: NM_148921, NP_683723

UniProt: Q52LD0

Pathways: EGFR Downregulation