EPS8 antibody (Middle Region)

Catalog No. ABIN503558

The Rabbit Polyclonal anti-EPS8 antibody has been validated for WB and IHC. It is suitable to detect EPS8 in samples from Human, Rat, Mouse, Dog, Cow, Pig, Horse and Rabbit.

Quick Overview for EPS8 antibody (Middle Region) (ABIN503558)

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Reactivity: Human, Rat, Mouse, Dog, Cow, Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EPS8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-EPS8 Antibody

Binding Specificity: Middle Region

Sequence: VSKVPANITR QNSSSSDSGG SIVRDSQRHK QLPVDRRKSQ MEEVQDELIH

Predicted Reactivity: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against EPS8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPS8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 822 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EPS8

Target: EPS8 (Epidermal Growth Factor Receptor Pathway Substrate 8 (EPS8))

Alternative Name: EPS8

Background: This gene encodes a member of the EPS8 family. This protein contains one PH domain and one SH3 domain. It functions as part of the EGFR pathway, though its exact role has not been determined. Highly similar proteins in other organisms are involved in the
Alias Symbols: -
Protein Interaction Partner: GRB2, RUNX1T1, BYSL, GOLGA8EP, C19orf25, C17orf59, INPP5J, BAIAP2, SMARCE1, HNRNPC, SUMO2, BAIAP2L1, ANKRD28, EPS8, SOX2, TPRN, PROSER2, NACC2, SCRN3, ARMC1, ADAM22, TDP2, GULP1, CTNNA3, ZZZ3, SF3B3, SLC27A4, BCKDK, RFXAP, NFKB2, MAP3K11, CXCL2, XRCC6, CS
Protein Size: 822

Molecular Weight: 92 kDa

Gene ID: 2059

NCBI Accession: NM_004447, NP_004438

UniProt: Q12929

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization