GNB1 antibody (N-Term)

Catalog No. ABIN503546

Product Details anti-GNB1 Antibody

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Zebrafish (Danio rerio), Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSELDQLRQE AEQLKNQIRD ARKACADATL SQITNNIDPV GRIQMRTRRT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against GNB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GNB1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 340 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-GNB1 antibody (ABIN503546)

Ueda, Nagae, Kozawa, Morishita, Kimura, Nagase, Ohara, Yoshida, Asano: "Heterotrimeric G protein betagamma subunits stimulate FLJ00018, a guanine nucleotide exchange factor for Rac1 and Cdc42." in: The Journal of biological chemistry, Vol. 283, Issue 4, pp. 1946-53, (2008) (PubMed).

Target Details for GNB1

Target: GNB1 (Guanine Nucleotide Binding Protein (G Protein), beta Polypeptide 1 (GNB1))

Alternative Name: GNB1 (GNB1 Products)

Background: Heterotrimeric guanine nucleotide-binding proteins (G proteins), which integrate signals between receptors and effector proteins, are composed of an alpha, a beta, and a gamma subunit. These subunits are encoded by families of related genes. GNB1 is a bet
Alias Symbols: -
Protein Interaction Partner: UBC, SUMO2, SUMO3, MTOR, RICTOR, RPTOR, WDR26, GNG2, GNG8, GNG12, GNGT1, GNG7, GNG5, GNG3, TBXA2R, ADRB2, PAN2, SVIL, NOL11, CYFIP1, VCAM1, NCF2, MTNR1A, EPHA7, AFP, ESR1, Htt, GNAI3, GNAI2, GNAI1, GNA11, ATP6V1B1, AKT1, MRGPRX1, RADIL, RASD1, ATXN10, RAS
Protein Size: 340

Molecular Weight: 37 kDa

Gene ID: 2782

NCBI Accession: NM_002074, NP_002065

UniProt: P62873

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome