Aurora Kinase C antibody (Middle Region)
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- Target See all Aurora Kinase C (AURKC) Antibodies
- Aurora Kinase C (AURKC)
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Binding Specificity
- Middle Region
- Reactivity
- Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Aurora Kinase C antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- TYDEKVDLWC IGVLCYELLV GYPPFESASH SETYRRILKV DVRFPLSMPL
- Predicted Reactivity
- Cow: 93%, Dog: 93%, Goat: 79%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
- Characteristics
- This is a rabbit polyclonal antibody against AURKC. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human AURKC
- Top Product
- Discover our top product AURKC Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 309 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).
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Nuclear translocation of CAM-associated protein activates transcription for long-term facilitation in Aplysia." in: Cell, Vol. 129, Issue 4, pp. 801-12, (2007) (PubMed).
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- Target
- Aurora Kinase C (AURKC)
- Alternative Name
- AURKC (AURKC Products)
- Background
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AURKC may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis.This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.
Alias Symbols: AIE2, AIK3, AurC, STK13, aurora-C, ARK3, SPGF5
Protein Interaction Partner: SRPK1, AURKB, HIST1H3A, INCENP, BIRC5, TACC2, UBC, HSP90AA1, BRCA1, LNX1, NEDD4L, NEDD4, CENPA,
Protein Size: 309 - Molecular Weight
- 34 kDa
- Gene ID
- 6795
- NCBI Accession
- NM_001015878, NP_001015878
- UniProt
- Q9UQB9
- Pathways
- Cell Division Cycle, Maintenance of Protein Location
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