RHEBL1 antibody (Middle Region)

Catalog No. ABIN503371

Product Details anti-RHEBL1 Antibody

Target: RHEBL1 (Ras Homolog Enriched in Brain Like 1 (RHEBL1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Guinea Pig, Horse, Rabbit, Rat, Cow, Dog, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RHEBL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TRVPVVLVGN KADLSPEREV QAVEGKKLAE SWGATFMESS ARENQLTQGI

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 86%

Characteristics: This is a rabbit polyclonal antibody against RHEBL1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RHEBL1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 183 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RHEBL1

Target: RHEBL1 (Ras Homolog Enriched in Brain Like 1 (RHEBL1))

Alternative Name: RHEBL1 (RHEBL1 Products)

Background: RHEBL1 binds GTP and exhibits intrinsic GTPase activity. It may activate NF-kappa-B-mediated gene transcription. RHEBL1 promotes signal transduction through FRAP1, activates RPS6KB1, and is a downstream target of the small GTPase-activating proteins TSC1 and TSC2.
Alias Symbols: FLJ25797, MGC34869, RHEBL1c
Protein Interaction Partner: APPL1, PRKAB2, MTOR, FHL3, TXNL4A, Blzf1, Traf2, BMPR1B, EIF4EBP1, SMAD1, SMAD2, SMAD4, TGFBR1, AKT1, ACVR1,
Protein Size: 183

Molecular Weight: 21 kDa

Gene ID: 121268

NCBI Accession: NM_144593, NP_653194

UniProt: Q8TAI7