Sec23 Homolog B antibody (Middle Region)

Catalog No. ABIN503318

Product Details anti-Sec23 Homolog B Antibody

Target: Sec23 Homolog B (SEC23B)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sec23 Homolog B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SFSLYPQFMF HLRRSPFLQV FNNSPDESSY YRHHFARQDL TQSLIMIQPI

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 92%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC23B. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SEC23B

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 767 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Sec23 Homolog B

Target: Sec23 Homolog B (SEC23B)

Alternative Name: SEC23B (SEC23B Products)

Background: SEC23B is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. SEC23B has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function SEC23B has been implicated in cargo selection and concentration.The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CDAII, CDAN2, CDA-II, HEMPAS
Protein Interaction Partner: UBC, HOXA3, SYNE4, PRRC1, DTX2, FATE1, CPSF7, SEC23B, SEC24D, SUMO2, SEC24C, ZYX, PXN, SRPK2, SRPK1, CSNK1A1, TMED9, UGT1A1, TMED1, TMED10, TMED2, KDELR1, MAN2A1, GALNT1, FN1, DAB2, SEC24B, SRSF3, CAND1, CUL3, SYK, SIRT7, FYCO1,
Protein Size: 767

Molecular Weight: 86 kDa

Gene ID: 10483

NCBI Accession: NM_006363, NP_006354

UniProt: Q15437