EIF2B1 antibody (C-Term)

Catalog No. ABIN503287

Product Details anti-EIF2B1 Antibody

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Pig, Rabbit, Cow, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF2B1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: ADTLKVAQTG QDLKEEHPWV DYTAPSLITL LFTDLGVLTP SAVSDELIKL

Predicted Reactivity: Cow: 79%, Dog: 79%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 79%, Rabbit: 79%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against EIF2B1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EIF2B1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 305 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for EIF2B1

Target: EIF2B1 (Eukaryotic Translation Initiation Factor 2B, Subunit 1 Alpha, 26kDa (EIF2B1))

Alternative Name: EIF2B1 (EIF2B1 Products)

Background: EIF2B1 belongs to the EIF-2B alpha/beta/delta subunits family. It catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Defects in EIF2B1 are a cause of leukoencephalopathy with vanishing white matter (VWM).
Alias Symbols: EIF-2B, EIF-2Balpha, EIF2B, EIF2BA, MGC117409, MGC125868, MGC125869
Protein Interaction Partner: RD3, WDYHV1, GORASP2, EIF2B1, UBC, GCD2, GCD6, EIF2B2, STK11, DCC, MRPL4, EIF2S2, EIF2S1, ARL4D, CREBBP, ADRB2, ADRA2B, ADRA2C, ADRA2A, EIF2B5, DCD, PDIA4, EIF2B3, HNRNPL, ARHGDIA,
Protein Size: 305

Molecular Weight: 34 kDa

Gene ID: 1967

NCBI Accession: NM_001414, NP_001405

UniProt: Q14232

Pathways: Methionine Biosynthetic Process