CYP4F12 antibody (C-Term)

Catalog No. ABIN503084

Product Details anti-CYP4F12 Antibody

Target: CYP4F12 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 12 (CYP4F12))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse, Sheep

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CYP4F12 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TVWPDPEVYD PFRFDPENSK GRSPLAFIPF SAGPRNCIGQ AFAMAEMKVV

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 93%, Sheep: 86%

Characteristics: This is a rabbit polyclonal antibody against CYP4F12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CYP4F12

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 524 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CYP4F12

Target: CYP4F12 (Cytochrome P450, Family 4, Subfamily F, Polypeptide 12 (CYP4F12))

Alternative Name: CYP4F12 (CYP4F12 Products)

Background: CYP4F12 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. Tt likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid, however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein likely localizes to the endoplasmic reticulum. When expressed in yeast the enzyme is capable of oxdizing arachidonic acid, however, its physiological function has not been determined. This gene is part of a cluster of cytochrome P450 genes on chromosome 19.
Alias Symbols: F22329_1
Protein Interaction Partner: SOD2, HSPA6, UBC,
Protein Size: 524

Molecular Weight: 60 kDa

Gene ID: 66002

NCBI Accession: NM_023944, NP_076433

UniProt: Q9HCS2

Pathways: Monocarboxylic Acid Catabolic Process