Vitamin D Receptor antibody (N-Term)

Catalog No. ABIN502646

Product Details anti-Vitamin D Receptor Antibody

Target: Vitamin D Receptor (VDR)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Vitamin D Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ILKRKEEEAL KDSLRPKLSE EQQRIIAILL DAHHKTYDPT YSDFCQFRPP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against VDR. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human VDR

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 427 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Vitamin D Receptor

Target: Vitamin D Receptor (VDR)

Alternative Name: VDR (VDR Products)

Target Type: Chemical

Background: VDR is the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarit
Alias Symbols: NR1I1
Protein Interaction Partner: MED12, MED24, BAZ1B, SMARCA4, RXRA, MED1, NCOA2, NSD1, NCOA1, SRPK1, PTPN3, Hr, NKD2, MMRN2, CDCA7L, CXXC5, UBC, RXRB, PRKCSH, PRCP, CFH, CCND3, MYC, MXD1, BRCA1, PSMC5, NCOR1, SRC, NCOA6, PPP1CC, CDK11B, NR1H2, RXRG, CASC4, GABARAPL1, GABARAPL2, CLASRP,
Protein Size: 427

Molecular Weight: 48 kDa

Gene ID: 7421

NCBI Accession: NM_000376, NP_000367

UniProt: P11473

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway