RRBP1 antibody (N-Term)

Catalog No. ABIN502586

Product Details anti-RRBP1 Antibody

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RRBP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: TDVAQSPEAP KQEAPAKKKS GSKKKGPPDA DGPLYLPYKT LVSTVGSMVF

Predicted Reactivity: Cow: 82%, Dog: 81%, Guinea Pig: 76%, Horse: 92%, Human: 100%, Mouse: 75%, Rabbit: 81%, Rat: 82%

Characteristics: This is a rabbit polyclonal antibody against RRBP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RRBP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 977 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RRBP1

Target: RRBP1 (Ribosome Binding Protein 1 (RRBP1))

Alternative Name: RRBP1 (RRBP1 Products)

Background: Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome.Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.
Alias Symbols: DKFZp586A1420, ES/130, ES130, FLJ36146, MGC157720, MGC157721, hES, RRp
Protein Interaction Partner: VCP, UBC, MDM2, LGR4, TARDBP, IQCB1, MAP1LC3A, PRKD2, SMAD9, MRPL53, SRPRB, CDV3, CHMP2A, PPIF, PQBP1, SCP2, RPS19, RPL38, RBMS1, PIN4, NDUFA7, HNRNPM, RAB8A, ILF3, HSPA1L, HSBP1, KLF5, CUL3, KIAA0101, SUMO1, Ndc80, ZWINT, ATF7IP, KIF5B, DSTN,
Protein Size: 977

Molecular Weight: 109 kDa

Gene ID: 6238

NCBI Accession: NM_001042576, NP_001036041