ANAPC10 antibody (N-Term)

Catalog No. ABIN502357

Product Details anti-ANAPC10 Antibody

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Horse, Cow, Rabbit, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ANAPC10 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MTTPNKTPPG ADPKQLERTG TVREIGSQAV WSLSSCKPGF GVDQLRDDNL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%

Characteristics: This is a rabbit polyclonal antibody against ANAPC10. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANAPC10

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 185 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ANAPC10 antibody (ABIN502357)

Nourry, Maksumova, Pang, Liu, Wang: "Direct interaction between Smad3, APC10, CDH1 and HEF1 in proteasomal degradation of HEF1." in: BMC cell biology, Vol. 5, pp. 20, (2004) (PubMed).

Target Details for ANAPC10

Target: ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

Alternative Name: ANAPC10 (ANAPC10 Products)

Background: ANAPC10 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and sub
Alias Symbols: APC10, DKFZP564L0562, DOC1
Protein Interaction Partner: ANAPC4, DCPS, UBC, ANAPC15, MDC1, TP53BP1, LIG4, ANAPC1, ANAPC7, ANAPC2, CDC16, CDC23, CDC27, Gm9174, Cdc20, Bub1b, PPP2R1A, APC2, ANAPC11, SMAD3, SMAD2, LRP1, LRP8, LRP2,
Protein Size: 185

Molecular Weight: 21 kDa

Gene ID: 10393

NCBI Accession: NM_014885, NP_055700

UniProt: Q9UM13

Pathways: M Phase