PON1 antibody (Middle Region)

Catalog No. ABIN502103

Product Details anti-PON1 Antibody

Target: PON1 (Paraoxonase 1 (PON1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Dog, Cow, Horse, Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PON1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: VVAEGFDFAN GINISPDGKY VYIAELLAHK IHVYEKHANW TLTPLKSLDF

Predicted Reactivity: Cow: 92%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PON1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PON1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 355 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-PON1 antibody (ABIN502103)

Penco, Buscema, Patrosso, Marocchi, Grossi: "New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background." in: BMC bioinformatics, Vol. 9, pp. 254, (2008) (PubMed).

Target Details for PON1

Target: PON1 (Paraoxonase 1 (PON1))

Alternative Name: PON1 (PON1 Products)

Background: PON1 hydrolyzes the toxic metabolites of a variety of organophosphorus insecticides. It is capable of hydrolyzing a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may mediate an enzymatic protection of low
Alias Symbols: ESA, PON, MVCD5
Protein Interaction Partner: CLU, SUMO4, APOA1, ALB,
Protein Size: 355

Molecular Weight: 40 kDa

Gene ID: 5444

NCBI Accession: NM_000446, NP_000437

UniProt: P27169