HEXIM2 antibody (N-Term)
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- Target See all HEXIM2 Antibodies
- HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))
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Binding Specificity
- N-Term
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Reactivity
- Human, Rat, Pig, Dog, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HEXIM2 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- MATPNQTACN AESPVALEEA KTSGAPGSPQ TPPERHDSGG SLPLTPRMES
- Predicted Reactivity
- Dog: 93%, Horse: 79%, Human: 100%, Pig: 86%, Rat: 100%
- Characteristics
- This is a rabbit polyclonal antibody against HEXIM2. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human HEXIM2
- Top Product
- Discover our top product HEXIM2 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 286 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- HEXIM2 (Hexamthylene Bis-Acetamide Inducible 2 (HEXIM2))
- Alternative Name
- HEXIM2 (HEXIM2 Products)
- Background
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HEXIM2 belongs to the HEXIM family. It is transcriptional regulator which functions as a general RNA polymerase II transcription inhibitor.In cooperation with 7SK snRNA, HEXIM2 sequesters P-TEFb in a large inactive 7SK snRNP complex preventing RNA polymerase II phosphorylation and subsequent transcriptional elongation.
Alias Symbols: FLJ32384, L3
Protein Interaction Partner: TCF12, CCDC36, HEXIM2, PRDM14, RNPS1, TADA3, SPRY2, SPRY1, PIN1, PIM1, MEOX2, GATA1, CDK9, RN7SK, HEXIM1, TERF2, TERF1, MEPCE, CCNT1,
Protein Size: 286 - Molecular Weight
- 31 kDa
- Gene ID
- 124790
- NCBI Accession
- NM_144608, NP_653209
- UniProt
- Q96MH2
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