UPF3A antibody (Middle Region)

Catalog No. ABIN502054

Product Details anti-UPF3A Antibody

Target: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UPF3A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QRYHVDDGRR HRAHHEPERL SRRSEDEQRW GKGPGQDRGK KGSQDSGAPG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against UPF3A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human UPF3A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for UPF3A

Target: UPF3A (UPF3 Regulator of Nonsense Transcripts Homolog A (UPF3A))

Alternative Name: UPF3A (UPF3A Products)

Background: UPF3A is part of a multiprotein post-splicing mRNP complex involved in both mRNA nuclear export and mRNA surveillance. UPF3A is involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. Binds spliced mRNA upstream of exon-exon j
Alias Symbols: HUPF3A, RENT3A, UPF3
Protein Interaction Partner: HTT, SMG1, HBB, APP, RNPS1, NXF1, SRRM1, TOPORS, PIGT, ALYREF, IFITM2, RBM8A, GSK3B, UPF1, UPF2, DCP2, UPF3B, EXOSC4, XRN1, EXOSC2, EXOSC10, PARN,
Protein Size: 476

Molecular Weight: 55 kDa

Gene ID: 65110

NCBI Accession: NM_023011, NP_075387

UniProt: Q9H1J1