RNMT antibody (N-Term)

Catalog No. ABIN501975

Product Details anti-RNMT Antibody

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Binding Specificity: N-Term

Reactivity: Human, Cow, Dog, Horse, Guinea Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RNMT antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ETEDVPKDKS STGDGTQNKR KIALEDVPEK QKNLEEGHSS TVAAHYNELQ

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Rabbit: 79%

Characteristics: This is a rabbit polyclonal antibody against RNMT. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RNMT

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 476 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RNMT

Target: RNMT (RNA Guanine-7 Methyltransferase (RNMT))

Alternative Name: RNMT (RNMT Products)

Background: RNMT belongs to the mRNA cap methyltransferase family. RNMT is a mRNA-capping methyltransferase that methylates the N7 position of the added guanosine to the 5'-cap structure of mRNAs. It binds RNA containing 5'-terminal GpppC.
Alias Symbols: DKFZp686H1252, KIAA0398, MET, RG7MT1, hCMT1c
Protein Interaction Partner: UBC, HECW2, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL5, RNGTT, KPNA2,
Protein Size: 476

Molecular Weight: 55 kDa

Gene ID: 8731

NCBI Accession: NM_003799, NP_003790

UniProt: O43148