CNOT3 antibody (C-Term)

Catalog No. ABIN501772

Product Details anti-CNOT3 Antibody

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNOT3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MMWFQRHEEP KTITDEFEQG TYIYFDYEKW GQRKKEGFTF EYRYLEDRDL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CNOT3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CNOT3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 753 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CNOT3

Target: CNOT3 (CCR4-NOT Transcription Complex, Subunit 3 (CNOT3))

Abstract: CNOT3 Products

Synonyms: LENG2 antibody, NOT3 antibody, NOT3H antibody, A930039N10Rik antibody, cnot3 antibody, zgc:55934 antibody, wu:fi20g07 antibody, fb73b06 antibody, fc17h07 antibody, wu:fb73b06 antibody, wu:fc17h07 antibody, zgc:92813 antibody, CNOT3 antibody, Afu2g02070 antibody, AO090011000479 antibody, CG8426 antibody, Dmel\\CG8426 antibody, NOT3.5 antibody, NOT3/5 antibody, Not3 antibody, not3 antibody, not3/5 antibody, leng2 antibody, not3h antibody, CCR4-NOT transcription complex subunit 3 antibody, CCR4-NOT transcription complex, subunit 3 antibody, CCR4-NOT transcription complex, subunit 3b antibody, CCR4-NOT transcription complex, subunit 3a antibody, CCR4-NOT transcription complex subunit 3 S homeolog antibody, CNOT3 antibody, Cnot3 antibody, cnot3b antibody, cnot3a antibody, AFUA_2G02070 antibody, NFIA_034440 antibody, ACLA_092760 antibody, PMAA_089540 antibody, AFLA_043060 antibody, TSTA_125290 antibody, ANI_1_738064 antibody, AOR_1_812054 antibody, Not3 antibody, cnot3 antibody, cnot3.S antibody

Background: CNOT3 is a protein component of CCR4-NOT protein complex. Yeast CCR4-NOT is a global regulator of RNA polymerase II transcription. It is comprised of yeast NOT1 to NOT5, yeast CCR4 and additional proteins like yeast CAF1.
Alias Symbols: KIAA0691, LENG2, NOT3, NOT3H
Protein Interaction Partner: UBC, NLK, SOX2, CNOT6L, CNOT6, ID3, HNRNPLL, CNOT1, RQCD1, CIRBP, Cnot3, SRRM1, CAND2, CNOT8, CAND1, CNOT2, CREBBP,
Protein Size: 753

Molecular Weight: 82 kDa

Gene ID: 4849

NCBI Accession: NM_014516, NP_055331

UniProt: O75175

Pathways: Stem Cell Maintenance