SSX5 antibody (Middle Region)

Catalog No. ABIN501489

Product Details anti-SSX5 Antibody

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSX5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GRLQGIFPKI TPEKPAEEGN DSKGVPEASG PQNNGKQLRP SGKLNTSEKV

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SSX5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SSX5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 229 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSX5

Target: SSX5 (Synovial Sarcoma, X Breakpoint 5 (SSX5))

Alternative Name: SSX5 (SSX5 Products)

Background: SSX5 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. The gene encoding SSX5 appears not to be involved in this type of chromosome translocation. The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This gene appears not to be involved in this type of chromosome translocation. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: MGC9494
Protein Interaction Partner: AGTRAP, ZSCAN1, PCBD2, NFE2,
Protein Size: 229

Molecular Weight: 26 kDa

Gene ID: 6758

NCBI Accession: NM_021015, NP_066295

UniProt: Q5JQ60