CHD1 antibody (Middle Region)

Catalog No. ABIN501271

Product Details anti-CHD1 Antibody

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Horse, Rabbit, Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHD1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RRKARAKKNK AMKSIKVKEE IKSDSSPLPS EKSDEDDDKL SESKSDGRER

Predicted Reactivity: Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 85%, Rabbit: 86%

Characteristics: This is a rabbit polyclonal antibody against CHD1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CHD1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1710 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHD1

Target: CHD1 (Chromodomain Helicase DNA Binding Protein 1 (CHD1))

Alternative Name: CHD1 (CHD1 Products)

Background: The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access
Alias Symbols: DKFZp686E2337
Protein Interaction Partner: FBXW11, UBC, ISG15, SPP1, SIRT7, ELAVL1, PAF1, SUMO2, SUMO1, MLLT1, HIST1H3A, CEBPA, HMGA1, SSRP1, SRSF3, SAFB, HIST3H3, HDAC1, H3F3B, NCOR1, BCLAF1, ARRB1,
Protein Size: 1710

Molecular Weight: 197 kDa

Gene ID: 1105

NCBI Accession: NM_001270, NP_001261

UniProt: O14646

Pathways: Chromatin Binding