BRD8 antibody (Middle Region)

Catalog No. ABIN501227

Product Details anti-BRD8 Antibody

Target: BRD8 (Bromodomain Containing 8 (BRD8))

Binding Specificity: Middle Region

Reactivity: Human, Rabbit, Dog, Horse, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRD8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: LRSQDLDEEL GSTAAGEIVE ADVAIGKGDE TPLTNVKTEA SPESMLSPSH

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 92%, Human: 100%, Rabbit: 85%

Characteristics: This is a rabbit polyclonal antibody against BRD8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human BRD8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1235 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for BRD8

Target: BRD8 (Bromodomain Containing 8 (BRD8))

Alternative Name: BRD8 (BRD8 Products)

Background: BRD8 interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator.The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.
Alias Symbols: SMAP, SMAP2, p120
Protein Interaction Partner: FSD2, MIS18A, SUMO2, UBC, SUMO1, SOX2, Chek2, DMAP1, KAT5, MAX, MYC, MORF4L1, MORF4L2, MRGBP, TP63, TP73, TP53, THRB, TRRAP, PPARG, WEE1, RXRA, ING3, RB1, KDM5A, RBL2,
Protein Size: 1235

Molecular Weight: 135 kDa

Gene ID: 10902

NCBI Accession: NM_139199, NP_631938

UniProt: Q9H0E9