FCGR1A antibody

Catalog No. ABIN490325

Product Details anti-FCGR1A Antibody

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Reactivity: Human, Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This FCGR1A antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro)), Neutralization (Neut), Blocking Reagent (BR)

Specificity: The mouse monoclonal antibody 10.1 recognizes alpha subunit of CD64/FcgammaRI, a 72 kD single chain type I glycoprotein, that is expressed on monocytes/macrophages, dendritic cells, and activated granulocytes. HLDA III, WS Code M-250.

Purification: Protein A purified

Immunogen: Rheumatoid synovial fluid cells and fibronectin purified human monocytes.

Type of Immunogen: Cells

Clone: 10-1

Isotype: IgG1

Application Details

Application Notes: Approved: Block, Flo, Func, ICC, IHC, IHC-Fr, IP, Neut, WB

Usage: Flow Cytometry: Recommended dilution - 5 μg/mL. Immunohistochemistry (paraffin sections): Application note - There can occur problems with paraformaldehyde fixation. Immunohistochemistry (frozen sections): Application note - There can occur problems with

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for FCGR1A

Target: FCGR1A (Fc Fragment of IgG, High Affinity Ia, Receptor (CD64) (FCGR1A))

Alternative Name: FCGR1A / CD64 (FCGR1A Products)

Background: Name/Gene ID: FCGR1A

Synonyms: FCGR1A, CD64A, CD64, CD64 antigen, FCG1, FcgammaRIa, IGFR1, IgG Fc receptor I, Fc-gamma receptor I A1, Fc-gamma RIA, FCGR1, Fc gamma receptor, Fc-gamma RI, FCRI

Gene ID: 2209

UniProt: P12314

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process