CD86 antibody (FITC)

Catalog No. ABIN490233

Product Details anti-CD86 Antibody (FITC)

Target: CD86

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This CD86 antibody is conjugated to FITC

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Immunocytochemistry (ICC), Blocking Reagent (BR), Neutralization (Neut)

Specificity: The rat monoclonal antibody GL-1 reacts with CD86 (B7-2), a 70-80 kD type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

Purification: Protein G purified

Immunogen: LPS-activated CBA/Cs mouse splenic B cells.

Type of Immunogen: Cells

Clone: GL1

Isotype: IgG2a

Application Details

Application Notes: Approved: Block, Flo, Func, ICC, IHC, IHC-Fr, IP, Neut

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. The reagent is designed for Flow Cytometry analysis. Suggested working concentration is 2 μg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide,  pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze. Product is photosensitive and should be protected from light.

Storage: 4 °C

Storage Comment: Store at 4°C. Do not freeze. Protect from light.

Target Details for CD86

Target: CD86

Alternative Name: CD86 (CD86 Products)

Background: Name/Gene ID: CD86

Synonyms: CD86, Activation B7-2 antigen, B7-2, B7.2, B70, CD86 Molecule, CTLA-4 counter-receptor B7.2, CD86 antigen, FUN-1, LAB72, BU63, CD28LG2, Ctla-4 counter-receptors b7.2

Gene ID: 942

UniProt: P42081

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation