EVI2B antibody

Catalog No. ABIN487440

Product Details anti-EVI2B Antibody

Target: EVI2B (Ecotropic Viral Integration Site 2B (EVI2B))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EVI2B antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Specificity: This antibody detects CD361.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Protein A affinity chromatography

Immunogen: Raji cells

Clone: MEM-216

Isotype: IgG1

Application Details

Application Notes: Flow cytometry. Positive control: Raji, Daudi, HL-60 cells, peripheral blood lymphcocytes (strongly positiveon CD19+ cells)Negative control: Jurkat, U-937 cells. Immunoprecipitation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for EVI2B

Target: EVI2B (Ecotropic Viral Integration Site 2B (EVI2B))

Alternative Name: CD361 / EVI2B (EVI2B Products)

Background: CD361, also known as EVI2B (Ecotropic Viral Integration site 2B) or EVDB, is a poorly characterized type I transmembrane protein, expressed from one of three genes embedded in intron 27b of the neurofibromatosis type 1 (NF1) gene. The DNA strand that is transcribed to produce CD361 is the complementary one to the strand encoding NF1. Murine homolog to human CD361 is associated with ecotropic viral insertions, which have been implicated in the expression of murine myeloid leukemias. CD361 has been also reported to be involved in melanocyte and keratinocyte differentiation. However, it is expressed mainly in peripheral blood and bone marrow.Synonyms: EVDB, Ecotropic viral integration site 2B protein homolog

Gene ID: 2124

UniProt: P34910