KAT2A antibody (AA 411-837)

Catalog No. ABIN487349

Product Details anti-KAT2A Antibody

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Binding Specificity: AA 411-837

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This KAT2A antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: The antibody recognizes human KAT2A (GCN5L2). Other species not tested.

Characteristics: Synonyms: Histone acetyltransferase KAT2A, Histone acetyltransferase GCN5, HsGCN5, HGCN5, Lysineacetyltransferase 2A, STAF97, General control of amino acid synthesis protein 5-like 2

Purification: Protein-G affinity chromatography

Immunogen: Recombinant human GCN5L2 (411-837aa) purified from E. coli

Clone: AT3G13

Isotype: IgG2a

Application Details

Application Notes: ELISA. Western blot (1: 250 - 1: 1000). Immunofluorescence (1: 250 - 1: 500).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4, containing 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for KAT2A

Target: KAT2A (K(lysine) Acetyltransferase 2A (KAT2A))

Alternative Name: KAT2A / GCN5L2 (KAT2A Products)

Background: GCN5L2, as known as GCN5 and KAT2A is the use of immunoprecipitated GCN5L2 for acetylation to provide the additional components important for acetylation. GCN5L2 can be one of the potential enzymes involved in acetylation in vivo. GCN5L2 is expressed predominantly in the embryo and newborn and is essential for normal embryonic development. Therefore, GCN5L2 appears to be important for differentiation of embryonic-derived preadipocytes. On the one hand, loss of GCN5L2 leads to high incidence of apoptosis in the GCN5L2 mutants that begins before the onset of morphological abnormality.Synonyms: General control of amino acid synthesis protein 5-like 2, HGCN5, Histone acetyltransferase GCN5, Histone acetyltransferase KAT2A, HsGCN5, Lysine acetyltransferase 2A, STAF97

Gene ID: 2648

UniProt: Q92830

Pathways: Chromatin Binding, Tube Formation