TBX3 antibody (Middle Region)
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- Target See all TBX3 Antibodies
- TBX3 (T-Box 3 (TBX3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Cow, Pig, Dog, Guinea Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This TBX3 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- VGTSNLKDLC PSEGESDAEA ESKEEHGPEA CDAAKISTTT SEEPCRDKGS
- Predicted Reactivity
- Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 92%
- Characteristics
- This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human TBX3
- Top Product
- Discover our top product TBX3 Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 743 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- TBX3 (T-Box 3 (TBX3))
- Alternative Name
- TBX3 (TBX3 Products)
- Background
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TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
Alias Symbols: TBX3-ISO, UMS, XHL
Protein Interaction Partner: CA8, AES, SOX2, Dlg4, ELAVL1, HDAC5, HDAC3, HDAC2, HDAC1, TOLLIP, TBX3,
Protein Size: 743 - Molecular Weight
- 79 kDa
- Gene ID
- 6926
- NCBI Accession
- NM_016569, NP_057653
- UniProt
- O15119
- Pathways
- Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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