RERE antibody (N-Term)

Catalog No. ABIN486972

Product Details anti-RERE Antibody

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Rabbit, Cow, Guinea Pig, Horse, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RERE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RPRRSCTLEG GAKNYAESDH SEDEDNDNNS ATAEESTKKN KKKPPKKKSR

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RERE. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RERE

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1566 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RERE

Target: RERE (Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE))

Alternative Name: RERE (RERE Products)

Background: RERE is a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. RERE co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development.This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARG, ARP, ATN1L, DNB1, FLJ38775, KIAA0458
Protein Interaction Partner: HDAC1, UBC, HDAC2, PRRC2B, KRTAP4-12, ALG13, EFEMP2, ZMYND8, RBFOX2, TRIM22, CBFA2T2, KAT6A, PRRC2A, PSMA3, PLSCR1, EFEMP1, ECM1, ATN1, ELAVL1, HIST2H3C, EHMT2, svp, Act5C, NR2E1, LZTR1, TRIP6,
Protein Size: 1566

Molecular Weight: 172 kDa

Gene ID: 473

NCBI Accession: NM_012102, NP_036234

UniProt: Q9P2R6

Pathways: Protein targeting to Nucleus