SPDEF/PSE antibody (Middle Region)

Catalog No. ABIN486951

Product Details anti-SPDEF/PSE Antibody

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Dog, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPDEF/PSE antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELCAMSEEQF RQRSPLGGDV LHAHLDIWKS AAWMKERTSP GAIHYCASTS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against SPDEF. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SPDEF

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 335 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SPDEF/PSE

Target: SPDEF/PSE (SPDEF) (Proximal Sequence Element 1 (SPDEF))

Alternative Name: SPDEF (SPDEF Products)

Background: PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA expression.PDEF is an ETS transcription factor expressed in prostate epithelial cells. It acts as an androgen-independent transactivator of PSA (MIM 176820) expression.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PDEF, RP11-375E1__A.3, bA375E1.3
Protein Interaction Partner: STK11, NKX3-1, PCGF2, AR,
Protein Size: 335

Molecular Weight: 37 kDa

Gene ID: 25803

NCBI Accession: NM_012391, NP_036523

UniProt: O95238