GTF2H4 antibody (N-Term)

Catalog No. ABIN486878

Product Details anti-GTF2H4 Antibody

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Guinea Pig, Dog, Cow, Goat, Rabbit, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GTF2H4 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ALWVKKEFSK AQEESTGLLS GLRIWHTQLL PGGLQGLILN PIFRQNLRIA

Predicted Reactivity: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against GTF2H4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GTF2H4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GTF2H4

Target: GTF2H4 (General Transcription Factor IIH, Polypeptide 4, 52kDa (GTF2H4))

Alternative Name: GTF2H4 (GTF2H4 Products)

Background: GTF2H4 belongs to the TFB2 family. It is a component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.
Alias Symbols: TFIIH, TFB2
Protein Interaction Partner: UBC, CDK7, RNF11, TP53, MNAT1, GTF2H3, GTF2H2, GTF2H1, ERCC3, CCNH, XBP1P1, MYC, GTF2E1, ERCC5, MED21, BTAF1, TBP, POLR2A, GTF2F1, GTF2B, BRCA1,
Protein Size: 462

Molecular Weight: 52 kDa

Gene ID: 2968

NCBI Accession: NM_001517, NP_001508

UniProt: Q92759

Pathways: DNA Damage Repair