Caspase 3 antibody (N-Term) (Alexa Fluor 488)
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- Target See all Caspase 3 (CASP3) Antibodies
- Caspase 3 (CASP3)
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Binding Specificity
- N-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Caspase 3 antibody is conjugated to Alexa Fluor 488
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Application
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Specificity
- Detects endogenous levels of the large fragment (17/19 kD) of activated caspase-3 resulting from cleavage adjacent to aspartic acid 175. Does not recognize full length caspase-3 or other cleaved caspases. Species cross-reactivity: Mouse and rat.
- Purification
- Protein A purified
- Immunogen
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Synthetic peptide corresponding to amino-terminal residues adjacent to Asp175 of human caspase-3 (KLH).
Type of Immunogen: Synthetic peptide - Isotype
- IgG
- Top Product
- Discover our top product CASP3 Primary Antibody
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- Application Notes
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Approved: ELISA, Flo (1:10), ICC (1:10), IF
Usage: Suitable for use in ELISA, Flow Cytometry, Immunocytochemistry, and Immunofluorescence. Flow Cytometry: 1:10. Immunocytochemistry: 1:10. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. - Comment
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- PBS, pH 7.2, <0.1 % sodium azide, 2.0 mg/mL BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Do not freeze.
- Storage
- 4 °C
- Storage Comment
- Store at 4°C. Do not freeze.
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- Target
- Caspase 3 (CASP3)
- Alternative Name
- CASP3 / Caspase 3 (CASP3 Products)
- Background
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Name/Gene ID: CASP3
Subfamily: Cysteine C14
Family: Protease
Synonyms: CASP3, Apopain, CASP-3, Caspase-3, CPP32B, CPP32, Cysteine protease CPP32, SCA-1, SREBP cleavage activity 1, Yama, Procaspase3, Caspase 3, CPP-32, PARP cleavage protease, Protein Yama - Gene ID
- 836
- UniProt
- P42574
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
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