CREB3L1 antibody (C-Term)

Catalog No. ABIN452874

Product Details anti-CREB3L1 Antibody

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Binding Specificity: AA 488-517, C-Term

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CREB3L1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Specificity: This antibody detects CREB3L1 / OASIS at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse.

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: KLH conjugated synthetic peptide between 488~517 amino acids from the C-terminal region of Human CREB3L1

Application Details

Application Notes: ELISA: 1/1,000. Western blot: 1/50-1/100. Flow cytometry: 1/10-1/50. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CREB3L1

Target: CREB3L1 (CAMP Responsive Element Binding Protein 3-Like 1 (CREB3L1))

Alternative Name: CREB3L1 / OASIS (CREB3L1 Products)

Synonyms: CREB3L1 antibody, OASIS antibody, Oasis antibody, diacylglycerol kinase-like antibody, cAMP responsive element binding protein 3 like 1 antibody, cAMP responsive element binding protein 3-like 1 antibody, LOC423198 antibody, CREB3L1 antibody, Creb3l1 antibody

Background: CREB3L1 is a transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. It is specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). It may play a role in gliosis. In vitro, it binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE.Synonyms: Cyclic AMP-responsive element-binding protein 3-like protein 1, Old astrocyte specifically-induced, PSEC0238, cAMP-responsive element-binding protein 3-like protein 1

Molecular Weight: 57005 Da

Gene ID: 90993

NCBI Accession: NP_443086

UniProt: Q96BA8

Pathways: Thyroid Hormone Synthesis, Chromatin Binding