ARPC1A antibody (C-Term)

Catalog No. ABIN452762

Product Details anti-ARPC1A Antibody

Target: ARPC1A (Actin Related Protein 2/3 Complex, Subunit 1A, 41kDa (ARPC1A))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC1A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects ARPC1A / SOP2L at C-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the C-terminal region of human ARPC1A

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000. Immunohistochemistry on paraffin sections 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for ARPC1A

Target: ARPC1A (Actin Related Protein 2/3 Complex, Subunit 1A, 41kDa (ARPC1A))

Alternative Name: ARPC1A / SOP2L (ARPC1A Products)

Background: ARPC1A is one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages.Synonyms: Actin-related protein 2/3 complex subunit 1A, SOP2-like protein

Molecular Weight: 41569 Da

Gene ID: 10552

NCBI Accession: NP_006400

UniProt: Q92747

Pathways: Regulation of Actin Filament Polymerization