APOL1 antibody (BH3 Domain)

Catalog No. ABIN452749

Product Details anti-APOL1 Antibody

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Binding Specificity: BH3 Domain

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APOL1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Apolipoprotein L1.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the BH3 Domain region of human APOL1

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for APOL1

Target: APOL1 (Apolipoprotein L, 1 (APOL1))

Alternative Name: Apolipoprotein L1 (Apo L1) (APOL1 Products)

Synonyms: APO-L antibody, APOL antibody, APOL-I antibody, FSGS4 antibody, wu:fa95b12 antibody, wu:fc30h04 antibody, si:rp71-1g18.12 antibody, apolipoprotein L1 antibody, apolipoprotein L, 1 antibody, APOL1 antibody, apol1 antibody

Background: APOL1 is a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver.Synonyms: APOL1, ApoL-I, Apolipoprotein L-I

Molecular Weight: 43974 Da

Gene ID: 8542

NCBI Accession: NP_001130012

UniProt: O14791