TNFSF14 antibody (Internal Region)
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- Target See all TNFSF14 Antibodies
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
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Binding Specificity
- Internal Region
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Reactivity
- Human
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This TNFSF14 antibody is un-conjugated
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Sequence
- c-HEVNPAAHLT GANS
- Specificity
- This antibody recognizes Human LIGHT. It is expected to recognize both reported isoforms (NP_003798.2, NP_742011.1). Other species not tested.
- Purification
- Affinity chromatography
- Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_003798.2, NP_742011.1.
- Top Product
- Discover our top product TNFSF14 Primary Antibody
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anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 62-240) antibody
TNFSF14 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 61-170) antibodyTNFSF14 Reactivity: Human WB, ELISA, IP, IHC (p) Host: Mouse Monoclonal 4E3 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 141-240) antibodyTNFSF14 Reactivity: Mouse, Rat WB, FACS, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 51-239) antibodyTNFSF14 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 62-240) antibodyTNFSF14 Reactivity: Human WB, IHC, IP, ICC Host: Mouse Monoclonal C1 unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239) antibodyTNFSF14 Reactivity: Human WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (Internal Region) antibodyVerified TNFSF14 Reactivity: Human WB, ELISA, IF Host: Goat Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 58-239) antibodyTNFSF14 Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 99-330) antibodyTNFSF14 Reactivity: Human ELISA, FACS Host: Rabbit Monoclonal DM170 unconjugated
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- Application Notes
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Peptide ELISA: 1/64000. Western blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- Target
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Alternative Name
- CD258 / LIGHT (TNFSF14 Products)
- Background
- LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors, the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).Synonyms: HVEM-L, HVEML, Herpesvirus entry mediator-ligand, TNFSF14, Tumor necrosis factor ligand superfamily member 14
- Gene ID
- 8740
- NCBI Accession
- NP_003798
- UniProt
- O43557
- Pathways
- Cancer Immune Checkpoints
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