Helicobacter Pylori antibody

Catalog No. ABIN452547

Product Details anti-Helicobacter Pylori Antibody

Target: Helicobacter Pylori (H. pylori)

Reactivity: Helicobacter pylori

Host: Mouse

Clonality: Monoclonal

Conjugate: This Helicobacter Pylori antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Characteristics: Synonyms: H. pylori CagA Gene Product, Helicobacter pylori cytokine associated gene A

Purification: Affinity Chromatography on Protein G.

Immunogen: A highly immunogenic 32Kd CagA fragment, recombinant.

Clone: 3C1

Isotype: IgG1

Application Details

Application Notes: ELISA: HP CagA antibody (Clone 3C1) can be used as Detection antibody. In Sandwich ELISA, anti-HP CagA antibody clone 10E9 (Cat#ABIN452543) and anti-HPCagA antibody clone 5H10 (Cat#ABIN452544) coated wells match with HRP conjugatedclone 3C1 to detect the recombinant antigen. Application of Clone 3C1 in Detection of CagA containing HP strain was not evaluated.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.0 without preservatives.

Preservative: Without preservative

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Helicobacter Pylori

Target: Helicobacter Pylori (H. pylori)

Alternative Name: Helicobacter Pylori (H. pylori Products)

Target Type: Virus

Background: Helicobacter pylori strains is known to exhibit a significant degree of diversity. The great variability in the H. pylori genome may explain why not all infected individuals suffer from ulcer. Some H. pylori strains contain particular pathogenic genes such as cytokine associated gene A (CagA), while others lack these genes. The CagA protein of H. pylori has been found to be associated with more severe clinical manifestations, such as ulcer disease and gastric cancer. Thus, discrimination between potentially virulent strains may be relevant.Synonyms: H. pylori