HLA DQ antibody (Biotin)

Catalog No. ABIN452105

Product Details anti-HLA DQ Antibody (Biotin)

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This HLA DQ antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity (Details): Species reactivity (tested):Human.

Characteristics: Synonyms: HLA-DQ, HLA class II histocompatibility antigen DQ, MHC class II antigen DQ, majorhistocompatibility complex class II

Purification: Affinity Chromatography.

Immunogen: Stimulated human B lymphocytes. The antigen is HLA-DQ. The epitope has not been further characterized.

Clone: FN81

Isotype: IgG2a

Application Details

Application Notes: Immunohistochemistry on Frozen Sections:
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 0.5 mL distilled water (= Stock solution).

Concentration: 0.2 mg/mL

Buffer: PBS, pH 7.2, with 0.05 % Kathon as preservative and 5 mg/mL BSA as stabilizer.

Preservative: Kathon CG

Precaution of Use: This product contains Kathon CG a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C. Stock solution or aliquots of stock solution can be kept frozen at -20 °C. Do not freeze working dilutions. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for HLA DQ

Target: HLA DQ (HLA-DQ) (MHC Class II HLA-DQ (HLA-DQ))

Alternative Name: HLA Class II DQ (HLA-DQ Products)

Background: HLA-DQ is an HLA class II antigen with homology to murine H-2A. HLA class II antigens are mainly expressed on specialized antigen presenting cells (APCs), dendritic cells, B-cells and macrophages. HLA class II antigen is presented on activated T-cells. HLA class II molecules present exogenously derived antigen to the T-cell receptor (TCR) on CD4+ T lymphocytes. Both chains in HLA-DQ are polymorphic. HLA-DQ is expressed after DR and DP during haemotopoietic progenitor cell development. It is strongly expressed in the thymic cortex.Synonyms: MHC Class II DQ