NFIC antibody (Middle Region)

Catalog No. ABIN406784

Product Details anti-NFIC Antibody

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NFIC antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: KSPFNSPSPQ DSPRLSSFTQ HHRPVIAVHS GIARSPHPSS ALHFPTTSIL

Cross-Reactivity: Cow (Bovine), Dog (Canine), Chicken, Human, Mouse (Murine), Pig (Porcine), Rat (Rattus)

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against NFIC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFIC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 499 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for NFIC

Target: NFIC (Nuclear Factor I/C (CCAAT-Binding Transcription Factor) (NFIC))

Alternative Name: NFIC (NFIC Products)

Background: Brg- or hBrm-associated factor (BAF) complexes, a chromatin-remodeling complex family of mammalian cells, facilitate transcriptional activity by remodeling nucleosome structure. Brg1 is the core subunit of Brg-associated factor complexes. BAF complexes can interact with NF1/CTF and RNAP II, and this interaction is closely dependent on the activation of gene transcription.
Alias Symbols: CTF, CTF5, MGC20153, NF-I, NFI
Protein Interaction Partner: HSP90AA1, TFAP4, Cebpb, ELAVL1, SUMO2, UBC, SMURF1, SMAD3, ZCCHC14, ZKSCAN7, TPD52L3, TKTL2, LLPH, NFIB, GLRX, CREBBP, RFX1, TLX1,
Protein Size: 499

Molecular Weight: 55 kDa

Gene ID: 4782

NCBI Accession: NM_205843, NP_995315

UniProt: Q6FI30