CDK5 antibody (N-Term)

Catalog No. ABIN406740

Product Details anti-CDK5 Antibody

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Pig, Sheep, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDK5 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SLASHVKNLD ENGLDLLSKM LIYDPAKRIS GKMALNHPYF NDLDNQIKKM

Predicted Reactivity: Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against CDK5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDK5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 292 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for CDK5

Target: CDK5 (Cyclin-Dependent Kinase 5 (CDK5))

Alternative Name: CDK5 (CDK5 Products)

Background: CDK5 is probably involved in the control of the cell cycle. It interacts with D1 and D3-type G1 cyclins. The protein can phosphorylate histone H1, tau, MAP2 and NF-H and NF-M. And it is also thought to interacts with p35 which activates the kinase.
Alias Symbols: PSSALRE
Protein Interaction Partner: CHFR, CCND2, CDKN1A, EGFR, UBC, DCLK3, CDK5, CCNE1, CDK5R1, CABLES1, CABLES2, STIP1, CDKN1B, CCND3, CCNB1, C2CD5, KIAA0195, FIBP, PPARG, CDK18, HSP90AB1, HSP90AA1, HIST1H1B, GLUD1, CDK3, CDC25B, CCT6A, CCNA2, CCT3, TCP1, CCT5, CDC37, CCT8, CCT2, CCT4, CCT
Protein Size: 292

Molecular Weight: 33 kDa

Gene ID: 1020

NCBI Accession: NM_004935, NP_004926

UniProt: Q00535

Pathways: Cell Division Cycle, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development, Synaptic Vesicle Exocytosis