ARPC2 antibody (N-Term)

Catalog No. ABIN406714

Product Details anti-ARPC2 Antibody

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MVLNVYCCFF QISDIQTMKI NQTILKEFIL VGFSVYPHVQ TFLFVVFFCL

Predicted Reactivity: Cow: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARPC2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ARPC2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 300 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ARPC2 antibody (ABIN406714)

Al Ghouleh, Rodríguez, Pagano, Csányi: "Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration." in: International journal of molecular sciences, Vol. 14, Issue 10, pp. 20220-35, (2013) (PubMed).

Target Details for ARPC2

Target: ARPC2 (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa (ARPC2))

Alternative Name: ARPC2 (ARPC2 Products)

Background: ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Alias Symbols: ARC34, PNAS-139, PRO2446, p34-Arc
Protein Interaction Partner: SUMO2, UBC, ARPC5L, AARSD1, PUS1, NIF3L1, THG1L, NSUN2, SH3GLB1, LAP3, TPRKB, TNPO3, ANP32B, ACTR2, ACTR3, ARPC1B, ARPC3, ARPC4, ARPC5, TOM1L1, FUBP1, SUMO1, TPD52L2, SH3GL1, RPA2, RPA1, RANGAP1, PRKACB, PRKACA, PPP2R5D, PFDN5, PPP1R12A, MTR, METTL1, CALU
Protein Size: 300

Molecular Weight: 33 kDa

Gene ID: 10109

NCBI Accession: NM_005731, NP_005722

UniProt: O15144

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization