WARS antibody (N-Term)

Catalog No. ABIN406710

Product Details anti-WARS Antibody

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WARS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EIDSAVKMLV SLKMSYKAAA GEDYKADCPP GNPAPTSNHG PDATEAEEDF

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against WARS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WARS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 471 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for WARS

Target: WARS (Tryptophanyl-tRNA Synthetase (WARS))

Alternative Name: WARS (WARS Products)

Synonyms: GAMMA-2 antibody, IFI53 antibody, IFP53 antibody, zgc:73274 antibody, wars antibody, MGC53671 antibody, WARS antibody, TrpRS antibody, WRS antibody, 85D-WRS antibody, CG9735 antibody, Dmel\\CG9735 antibody, WRS-85D antibody, l(3)03559 antibody, l(3)03560 antibody, l(3)3559 antibody, gamma-2 antibody, ifi53 antibody, ifp53 antibody, GB14934 antibody, ECK3371 antibody, JW3347 antibody, tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase S homeolog antibody, Tryptophanyl-tRNA synthetase antibody, tryptophanyl-tRNA synthetase L homeolog antibody, tryptophan--tRNA ligase, cytoplasmic antibody, WARS antibody, wars antibody, wars.S antibody, Wars antibody, TrpRS antibody, wars.L antibody, LOC727582 antibody, trpS antibody, trpS2 antibody

Background: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Two forms of tryptophanyl-tRNA synthetase exist, a cytoplasmic form, named WARS, and a mitochondrial form, named WARS2. Tryptophanyl-tRNA synthetase (WARS) catalyzes the aminoacylation of tRNA(trp) with tryptophan and is induced by interferon. Tryptophanyl-tRNA synthetase belongs to the class I tRNA synthetase family. Four transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: GAMMA-2, IFI53, IFP53
Protein Interaction Partner: UBC, SUMO2, CDC34, CALU, ADSL, AARS, CTPS2, HERC4, NT5C2, FKBP9, EHD1, GNPDA1, GTF3C4, USP5, XPNPEP1, RAD23A, TWF1, PCNA, NUCB1, KTN1, GTF2I, CD81, LIG4, TRIM25, GART, APP, ISG15, TERF1, SIRT7, PSMA3, DNMT3B, DCAF13, DDA1, GBAS, CDK2AP2, MDH2, EEF1A1,
Protein Size: 471

Molecular Weight: 52 kDa

Gene ID: 7453

NCBI Accession: NM_004184, NP_004175

UniProt: P23381