ACADS antibody (Middle Region)

Catalog No. ABIN406378

Product Details anti-ACADS Antibody

Target: ACADS (Acads) (Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Horse, Rabbit, Guinea Pig, Zebrafish (Danio rerio), Cow, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACADS antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: FTSGDKIGCF ALSEPGNGSD AGAASTTARA EGDSWVLNGT KAWITNAWEA

Predicted Reactivity: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ACADS. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACADS

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 412 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-ACADS antibody (ABIN406378)

Tein, Elpeleg, Ben-Zeev, Korman, Lossos, Lev, Lerman-Sagie, Leshinsky-Silver, Vockley, Berry, Lamhonwah, Matern, Roe, Gregersen: "Short-chain acyl-CoA dehydrogenase gene mutation (c.319C>T) presents with clinical heterogeneity and is candidate founder mutation in individuals of Ashkenazi Jewish origin." in: Molecular genetics and metabolism, Vol. 93, Issue 2, pp. 179-89, (2008) (PubMed).

Target Details for ACADS

Target: ACADS (Acads) (Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads))

Alternative Name: ACADS (Acads Products)

Background: ACADS is a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ACAD3, SCAD
Protein Interaction Partner: IRF7,
Protein Size: 412

Molecular Weight: 42 kDa

Gene ID: 35

NCBI Accession: NM_000017, NP_000008

UniProt: P16219

Pathways: Monocarboxylic Acid Catabolic Process